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[年龄作为急性胰腺炎严重程度的预后因素的价值]

[The value of age as a prognostic factor in the severity of acute pancreatitis].

作者信息

Martínez Sempere J, Sánchez Payá J, Palazón Azorín J M, Gutiérrez Casbas A, Pérez-Mateo Regadera M

机构信息

Servicio de Medicina Interna, Hospital General, Alicante.

出版信息

Gastroenterol Hepatol. 1997 Feb;20(2):49-54.

PMID:9072203
Abstract

Age has been considered as a risk factor for the development of complications in acute pancreatitis. To confirm the above a retrospective study was designed including 526 cases of acute pancreatitis which were classified, according to age, into two groups: group I: > 65 years, and group II: < or = 65 years. The evolution of pancreatitis was classified as mild or severe according to the criteria of the Atlanta Meeting. Furthermore, other variables which may influence in the development of complications, such as the etiology or the presence of other associated diseases at the time of the appearance of pancreatitis were taken into account. On comparison of the severity of pancreatitis in both groups significant differences were only found in the appearance of acute renal failure. A relationship was, however, observed between the existence of certain diseases (arterial hypertension, diabetes mellitus and chronic renal failure) present at the time of the appearance of acute pancreatitis and the development of complications of the latter. In addition, on comparing the epidemiologic and etiologic data of the two groups, it was found that acute pancreatitis in the elderly is more often of biliary etiology, is more frequent in females and is usually accompanied by other diseases at the time of appearance. Age in itself is not a risk factor for the development of complications in acute pancreatitis. The association of diseases at the time of the initiation of pancreatitis implies a worse prognosis.

摘要

年龄被视为急性胰腺炎发生并发症的一个危险因素。为证实上述观点,设计了一项回顾性研究,纳入526例急性胰腺炎病例,根据年龄将其分为两组:第一组:>65岁,第二组:≤65岁。根据亚特兰大会议的标准,将胰腺炎的进展分为轻度或重度。此外,还考虑了其他可能影响并发症发生的变量,如胰腺炎出现时的病因或是否存在其他相关疾病。比较两组胰腺炎的严重程度时,仅在急性肾衰竭的发生方面发现了显著差异。然而,观察到急性胰腺炎出现时存在某些疾病(动脉高血压、糖尿病和慢性肾衰竭)与后者并发症的发生之间存在关联。此外,比较两组的流行病学和病因学数据时发现,老年急性胰腺炎更常由胆源性病因引起,女性更为常见,且发病时通常伴有其他疾病。年龄本身并非急性胰腺炎发生并发症的危险因素。胰腺炎发病时合并其他疾病意味着预后较差。

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