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[煤矿矿工肾素 - 血管紧张素 - 醛固酮系统及水盐代谢变化]

[Changes in the renin-angiotensin-aldosterone system and water-salt exchange in mining workers in coal mines].

作者信息

Rebrov B A

出版信息

Lik Sprava. 1996 Jul-Sep(7-9):89-92.

PMID:9072279
Abstract

Blood and urine content of electrolytes and creatinine was determined in 76 essentially healthy miners before and after work shift, as was activity of plasma renin, blood plasma level of aldosterone and its urinary excretion, with the aid of radioimmunoassay. The greatest activity of the renin-angiotensine-aldosterone system (RAAS) occurred in those individuals engaged in hard physical labour under most harsh conditions of underground workings, this being recordable not only is response to the load but also from the very start. Controls and miners doing jobs of medium-level strenuousness demonstrated changes in the correlations between RAAS and water-salt balance after the work shift as compared with those before the work shift, while in those miners engaged in hard work correlations RAAS-water-salt exchange remained practically the same throughout the study.

摘要

在76名基本健康的矿工中,于轮班前和轮班后测定了血液和尿液中的电解质及肌酐含量,同时借助放射免疫分析法测定了血浆肾素活性、血浆醛固酮水平及其尿排泄量。肾素 - 血管紧张素 - 醛固酮系统(RAAS)的最大活性出现在那些在地下工作最恶劣条件下从事重体力劳动的个体中,这不仅在对负荷的反应中可记录到,而且从一开始就可记录到。对照组和从事中等强度工作的矿工在轮班后与轮班前相比,RAAS与水盐平衡之间的相关性发生了变化,而在从事繁重工作的矿工中,整个研究过程中RAAS与水盐交换的相关性实际上保持不变。

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