Rebrov B A, Lymar' S P
Lik Sprava. 1999 Jul(5):135-7.
In a study into the condition of central hemodynamics and water-salt metabolism made in 85 essentially healthy underground miners working in a coal mine those miners greater than 40 years old exhibited an increase in the peripheral vascular resistance together with a decrease in the power of the left ventricle and a rise in energy expenditure on blood redirection, which fact led to lowering of both volume- and velocity-related parameters for hemodynamics. Worsening of hemodynamic indexes was noted to be going on parallel to changes in water-salt metabolism: workers beyond thirty years of age showed an augmentation of the level of Na+ and creatinine in blood plasma, those greater than 40 years old demonstrated a reduction in urine creatinine, in those beyond fifty years of age glomerular filtration rate was found to be on decrease with fractional excretion of Na+ being on the increase.
在一项针对85名在煤矿工作的基本健康的地下矿工的中心血流动力学和水盐代谢状况的研究中，40岁以上的矿工表现出外周血管阻力增加，同时左心室功能下降，血液重新分布的能量消耗增加，这一事实导致血流动力学中与容量和速度相关的参数均降低。血流动力学指标的恶化与水盐代谢的变化同时发生：30岁以上的工人血浆中Na+和肌酐水平升高，40岁以上的工人尿肌酐降低，50岁以上的工人肾小球滤过率下降，Na+分数排泄增加。
