Shaw P K, Brodsky R E, Lyman D O, Wood B T, Hibler C P, Healy G R, Macleod K I, Stahl W, Schultz M G
Ann Intern Med. 1977 Oct;87(4):426-32. doi: 10.7326/0003-4819-87-4-426.
Three hundred fifty residents of Rome, New York, had laboratory-confirmed cases of giardiasis between 1 November 1974 and 7 June 1975. A random household survey showed an overall attack rate for giardiasis (defined as a diarrheal illness of 5 days or more) of 10.6%. A significant association was discovered between having giardiasis and using city water and between having illness and drinking 1 or more glasses of water a day. The presence of human settlements in the Rome watershed area suggested that the water supply could have been contaminated by untreated human waste. The infectivity of municipal water was confirmed by producing giardiasis in specific pathogen-free dogs fed sediment samples of raw water obtained from an inlet of a city reservoir. A microscopic examination of the water sediments uncovered a Giardia lamblia cyst in one sample. This was the first time that a G. lamblia cyst has been found in municipal water in an epidemic and the first time that such water has been shown to infect laboratory animals.
1974年11月1日至1975年6月7日期间，纽约州罗马市有350名居民经实验室确诊感染贾第虫病。一项随机家庭调查显示，贾第虫病（定义为持续5天或更长时间的腹泻疾病）的总体发病率为10.6%。研究发现，感染贾第虫病与使用城市供水之间、患病与每天饮用一杯或更多杯水之间存在显著关联。罗马流域地区有人口聚居，这表明供水可能受到未经处理的人类粪便污染。通过给食用从城市水库进水口采集的原水沉积物样本的无特定病原体犬诱发贾第虫病，证实了市政供水具有传染性。对水沉积物进行显微镜检查时，在一个样本中发现了蓝氏贾第鞭毛虫囊肿。这是首次在疫情中于市政供水中发现蓝氏贾第鞭毛虫囊肿，也是首次证明这种水会感染实验动物。
