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[免疫功能正常患者的颈淋巴结炎:戈登分枝杆菌是病因吗?]

[Cervical lymphadenitis in an immunocompetent patient: Mycobacterium gordonae as the cause?].

作者信息

Fleisch F, Pfyffer G E, Thüring C, Lüthy R, Weber R

机构信息

Abteilung Infektionskrankheiten und Spitalhygiene, Universitätsspital Zürich.

出版信息

Dtsch Med Wochenschr. 1997 Jan 17;122(3):51-3. doi: 10.1055/s-2008-1047576.

Abstract

HISTORY AND FINDINGS

A 76-year-old man went to an ENT outpatient clinic because of stabbing pain in the left throat and difficult swallowing. He was found to have tonsillitis on the left and cervical lymphadenitis. The symptoms regressed on treatment with amoxycillin and clavulanic acid, but the cervical lymphadenitis persisted. Fine-needle biopsy of the cervical swelling was not diagnostic. Computed tomography of the neck showed an encapsulated liquid space-occupying lesion with infiltration of surrounding soft tissues.

TREATMENT AND COURSE

The cervical lymph-node mass was excised and histologically found to contain epithelioid granulomas with a few giant cells and scattered centrally caseous necroses. Tuberculostatic treatment was started; drainage fluid from the wound grew acid-fast bacilli, identified by gene probe as Mycobacterium gordonae.

CONCLUSIONS

Mycobacterium gordonae is ubiquitous in the environment and is being identified ever more frequently in microbiological laboratories, usually as contaminant. It rarely causes infections of soft tissues and the lungs or systemically.

摘要

病史与检查结果

一名76岁男性因左侧咽喉刺痛及吞咽困难前往耳鼻喉科门诊就诊。检查发现他患有左侧扁桃体炎和颈部淋巴结炎。经阿莫西林克拉维酸治疗后症状有所缓解,但颈部淋巴结炎仍持续存在。颈部肿物的细针穿刺活检未能明确诊断。颈部计算机断层扫描显示有一个包膜完整的液性占位性病变,周围软组织有浸润。

治疗过程

切除颈部淋巴结肿块,组织学检查发现其中含有上皮样肉芽肿,伴有少量巨细胞及散在的中央干酪样坏死。开始进行抗结核治疗;伤口引流液培养出抗酸杆菌,经基因探针鉴定为戈登分枝杆菌。

结论

戈登分枝杆菌在环境中普遍存在,在微生物实验室中越来越频繁地被鉴定出来,通常作为污染物。它很少引起软组织、肺部或全身性感染。

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