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[使用安吉尔奇克假体治疗食管反流:26例患者的随访分析]

[Treatment of esophageal reflux by insertion of Angelchik prosthesis: analysis of the follow-up in 26 patients].

作者信息

Franchello A, Olivero G, Mao P, Scavarda B, Bertoldo U, Deriu L

机构信息

Istituto di Chirurgia d'Urgenza, Università degli Studi, Torino.

出版信息

Minerva Chir. 1996 May;51(5):273-8.

PMID:9072735
Abstract

The authors report a retrospective analysis of the immediate and long-term results of treatment of gastroesophageal reflux refractory to medical therapy using the insertion of Angelchik's prosthesis in a group of 26 patients operated at the Institute of Emergency Surgery of Turin University from January 1980 to December 1993. All patients underwent pre- and postoperative endoscopy and were then controlled using esophagogastric X-ray, esophagogastroscopy, esophageal manometry and pH-metry in the event of disorders of esophageal motility. Operative mortality was nil and no major surgical complications were reported. Postoperative endoscopy showed the resolution of esophagitis in 23 patients (88.4%); symptoms of slight esophagitis persisted in 2 cases, and moderate esophagitis in another. Eighteen patients were monitored over time with a minimum follow-up of more than 2 years: persistent dysphagia appeared in 3 cases (16.6%), and in one patient this led to the need for endoscopic dilatations. Two patients (11.1%) presented "gas bloat syndrome" which gradually improved. It was never necessary to remove the device. No cases were observed of erosion, migration or destruction of the prosthesis. Follow-up exceeded 10 years in 7 patients, at present asymptomatic. Angelchik's prosthesis proved to be efficacious, rapid and simple to insert, and characterised by a lower morbidity rate and shorter postoperative course. The incidence of postoperative dysphagia makes only it is use indicated only in patients with a high operative risk, obese subjects and in case of recidivation of reflux after fundoplication.

摘要

作者报告了一项回顾性分析,该分析针对1980年1月至1993年12月在都灵大学急诊外科接受手术的26例患者,这些患者因药物治疗无效的胃食管反流而使用安吉尔奇克假体进行治疗,分析了其近期和远期治疗结果。所有患者均在术前和术后接受了内镜检查,随后在出现食管动力障碍时,使用食管胃X线检查、食管胃镜检查、食管测压和pH值测定进行监测。手术死亡率为零,未报告重大手术并发症。术后内镜检查显示,23例患者(88.4%)的食管炎得到缓解;2例患者仍有轻度食管炎症状,另1例为中度食管炎。对18例患者进行了长期随访,最短随访时间超过2年:3例患者(16.6%)出现持续性吞咽困难,其中1例患者需要进行内镜扩张。2例患者(11.1%)出现“气体膨胀综合征”,但逐渐好转。从未有必要取出该装置。未观察到假体侵蚀、移位或损坏的病例。7例患者的随访时间超过10年,目前无症状。安吉尔奇克假体被证明是有效、快速且插入简单的,其特点是发病率较低,术后病程较短。术后吞咽困难的发生率使得该假体仅适用于手术风险高的患者、肥胖患者以及胃底折叠术后反流复发的情况。

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