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碳氢化合物的毒理学研究——碘美克斯

Toxicological studies on hydrocarbons--Iomex.

作者信息

Rao G S, Dhasmana A, Kaw J L, Pandya K P, Zaidi S H

出版信息

Arch Environ Contam Toxicol. 1977;6(1):57-62. doi: 10.1007/BF02097749.

DOI:10.1007/BF02097749
PMID:907375
Abstract

Hematological changes and concurrent enzymatic activities in various tissues were determined in rats injected parentally with Iomex, a petroleum derivate and proposed weedicide. Among the hematological parameters studied only the differential leucocytic count showed significant alterations. This was indicated by a significant decrease in the number of lymphocytes and an increase in those of neutrophils. Significant differences were not observed in the levels of acid phosphatase, glutamic oxaloacetic, and glutamic pyruvate transaminase activities in brain and liver of the experimental group of animals.

摘要

给大鼠经肠胃外注射一种石油衍生物及拟用除草剂碘麦司,测定其血液学变化以及不同组织中的相关酶活性。在所研究的血液学参数中,只有白细胞分类计数显示出显著变化。这表现为淋巴细胞数量显著减少,中性粒细胞数量增加。在实验组动物的脑和肝中,酸性磷酸酶、谷草转氨酶和谷丙转氨酶的活性水平未观察到显著差异。

相似文献

1
Toxicological studies on hydrocarbons--Iomex.碳氢化合物的毒理学研究——碘美克斯
Arch Environ Contam Toxicol. 1977;6(1):57-62. doi: 10.1007/BF02097749.
2
Acute toxicity of Iomex--a petroleum weedicide.碘草灭(一种石油类除草剂)的急性毒性
Bull Environ Contam Toxicol. 1975 Aug;14(2):241-9. doi: 10.1007/BF01701321.
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Toxic effects of Iomex on rat after repeated oral administration.碘美辛重复口服给药对大鼠的毒性作用。
Toxicology. 1977 Feb;7(1):57-68. doi: 10.1016/0300-483x(77)90038-5.
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Intermediary metabolism in a lizard, Calotes versicolor: role of thyroid hormones.变色树蜥的中间代谢:甲状腺激素的作用
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Pol J Pharmacol Pharm. 1975 Jul-Aug;27(4):357-64.
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[Effect of hydrocortisone and insulin on tissue enzymes in conditions of hypothyreosis].[氢化可的松和胰岛素对甲状腺功能减退症情况下组织酶的影响]
Farmakol Toksikol. 1973 Jan-Feb;36(1):89-92.

引用本文的文献

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Successful outcome after intravenous gasoline injection.静脉注射汽油后的成功结果。
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Distribution of Fe59 in benzene and iomex treated rats.苯和碘美酸处理大鼠中Fe59的分布
Arch Toxicol. 1979 Apr 23;42(1):43-9. doi: 10.1007/BF00351823.

本文引用的文献

1
Acute hemolytic anemia due to naphthalene poisoning; a clinical and experimental study.萘中毒所致急性溶血性贫血;一项临床与实验研究。
J Am Med Assoc. 1949 Sep 17;141(3):185-90. doi: 10.1001/jama.1949.02910030015004.
2
Toxicological studies on hydrocarbons. III. The biochemorphology of the phenylalkanes and phenylalkenes.碳氢化合物的毒理学研究。III. 苯烷和苯烯烃的生物化学形态学。
AMA Arch Ind Health. 1959 Apr;19(4):403-18.
3
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
一种测定血清谷草转氨酶和谷丙转氨酶的比色法。
Am J Clin Pathol. 1957 Jul;28(1):56-63. doi: 10.1093/ajcp/28.1.56.
4
Hydrocarbon pneumonitis.烃类肺炎
Pediatr Clin North Am. 1957 Feb:243-53. doi: 10.1016/s0031-3955(16)30484-9.
5
Toxicological studies of certain alkylated benzenes and benzene; experiments on laboratory animals.某些烷基苯和苯的毒理学研究;对实验动物的实验
AMA Arch Ind Health. 1956 Oct;14(4):387-98.
6
Health of the petroleum worker.石油工人的健康。
AMA Arch Ind Health. 1955 Feb;11(2):126-31.
7
Toxicological studies on p-tertiary-butyltoluene.对叔丁基甲苯的毒理学研究。
AMA Arch Ind Hyg Occup Med. 1954 Mar;9(3):227-44.
8
Possible mechanisms of drug-induced tissue lesions.药物诱导组织损伤的可能机制。
Chem Biol Interact. 1971 Aug;3(4):247. doi: 10.1016/0009-2797(71)90045-7.
9
Phenobarbital-induced protection against toxicity of toluene and benzene in the rat.
Toxicol Appl Pharmacol. 1971 Sep;20(1):30-43. doi: 10.1016/0041-008x(71)90086-x.
10
Pathology of erythroblastic mitosis in occupational benzenic erythropathy and erythrema. In vivo and in vitro studies.职业性苯中毒性红细胞增多症和红斑中幼红细胞有丝分裂的病理学。体内和体外研究。
Bibl Haematol. 1970;35:1-188.