Knolle H, Heinicke G, Matzel W
Arch Geschwulstforsch. 1977;47(3):210-9.
Cytologic examinations of pleural exudate and cyto-histological examination of biopsies taken from the pleura give useful contributions in the differential diagnosis of primary chronic nonspecific pleurisy. In the early stage of disease the cellular findings are characteristic and enable easy differentiation of mesothelioma. Later on in primary chronic nonspecific pleurisy alterations of mesothelial cells can be seen which mimic tumorous cells and may be erroneously taken for mesothelioma cells. Quantity and quality of these alterations of nucleus and cytoplasma of mesothelial cells in primary chronic nonspecific pleurisy can be distinguished from tumor cells of mesothelioma by critical evaluation in the majority of cases.
对胸腔积液进行细胞学检查以及对取自胸膜的活检组织进行细胞组织学检查，在原发性慢性非特异性胸膜炎的鉴别诊断中发挥着重要作用。在疾病早期，细胞检查结果具有特征性，有助于轻松鉴别间皮瘤。在原发性慢性非特异性胸膜炎后期，可观察到间皮细胞的改变，这些改变类似肿瘤细胞，可能会被误诊为间皮瘤细胞。在大多数情况下，通过严格评估，原发性慢性非特异性胸膜炎中间皮细胞核与细胞质这些改变的数量和质量可与间皮瘤的肿瘤细胞相区分。
