Lu D W, Azuara-Blanco A, Katz L J
William and Anna Goldberg Glaucoma Service and Research Laboratories, Wills Eye Hospital, Jefferson Medical College, Philadelphia, PA 19107, USA.
Ophthalmic Surg Lasers. 1997 Mar;28(3):244-5.
It has been shown that mitomycin-C increases the success rate of trabeculectomy; however, a rise in the incidence of postoperative complications has also been reported. Consequently, the use of antimetabolite is usually reserved for patients who are at high risk of surgical failure or for patients with advanced glaucoma in whom low intraocular pressure is desired. This report describes a patient who suffered severe visual loss which was a direct result of hypotonous maculopathy after trabeculectomy with mitomycin-C and various other complications from the subsequent interventions.
已经表明丝裂霉素-C可提高小梁切除术的成功率；然而，也有术后并发症发生率上升的报道。因此，抗代谢药物的使用通常仅限于手术失败风险高的患者或期望获得低眼压的晚期青光眼患者。本报告描述了一名患者，其在接受丝裂霉素-C小梁切除术后因低眼压性黄斑病变以及后续干预的各种其他并发症而遭受严重视力丧失。
