Appiah R, Hiller S, Caspary L, Alexander K, Creutzig A
Medizinische Hochschule Hannover, Department of Angiology, Germany.
J Intern Med. 1997 Feb;241(2):119-24. doi: 10.1046/j.1365-2796.1997.91105000.x.
Evaluation of the effects of a standardized acupuncture treatment in primary Raynaud's syndrome.
A controlled randomized prospective study.
A winter period of 23 weeks, angiological clinic of Hannover Medical School.
Thirty-three patients with primary Raynaud's syndrome (16 control, 17 treatment).
The patients of the treatment group were given seven acupuncture treatments during the weeks 10 and 11 of the observation period.
All patients kept a diary throughout the entire observation period noting daily frequency, duration and severity of their vasospastic attacks. A local cooling test combined with nailfold capillaroscopy was performed for all patients at baseline (week 1) and in weeks 12 and 23, recording flowstop reactions of the nailfold capillaries.
The treated patients showed a significant decrease in the frequency of attacks from 1.4 day-1 to 0.6 day-1, P < 0.01 (control 1.6 to 1.2, P = 0.08). The overall reduction of attacks was 63% (control 27%, P = 0.03). The mean duration of the capillary flowstop reaction decreased from 71 to 24 s (week 1 vs. week 12, P = 0.001) and 38 s (week 1 vs. week 23, P = 0.02) respectively. In the control group the changes were not significant.
These findings suggest that traditional Chinese acupuncture is a reasonable alternative in treating patients with primary Raynaud's syndrome.
评估标准化针刺治疗对原发性雷诺综合征的疗效。
一项对照随机前瞻性研究。
汉诺威医学院血管病门诊,为期23周的冬季时段。
33例原发性雷诺综合征患者(16例对照,17例治疗)。
治疗组患者在观察期的第10周和第11周接受7次针刺治疗。
所有患者在整个观察期内均记日记,记录血管痉挛发作的每日频率、持续时间和严重程度。在基线时(第1周)以及第12周和第23周对所有患者进行局部冷刺激试验并结合甲襞毛细血管镜检查,记录甲襞毛细血管的血流停止反应。
治疗组患者发作频率从1.4次/天显著降至0.6次/天,P<0.01(对照组从1.6次降至1.2次,P = 0.08)。发作次数总体减少63%(对照组为27%,P = 0.03)。毛细血管血流停止反应的平均持续时间分别从71秒降至24秒(第1周与第12周相比,P = 0.001)和38秒(第1周与第23周相比,P = 0.02)。对照组的变化不显著。
这些发现表明,传统中医针刺疗法是治疗原发性雷诺综合征患者的一种合理替代方法。