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他莫昔芬对体外雌二醇诱导的小鼠囊胚表面被膜变化的抑制作用。

Tamoxifen inhibition of an in vitro oestradiol-induced surface coat change on mouse blastocysts.

作者信息

Bloxham P A, Pugh D M

出版信息

Br J Pharmacol. 1977 Aug;60(4):517-9. doi: 10.1111/j.1476-5381.1977.tb07529.x.

DOI:10.1111/j.1476-5381.1977.tb07529.x
PMID:907866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1667391/
Abstract
  1. Eighty-nine hour post-coitus mouse blastocysts cultured in the presence of oestradiol-17beta underwent a histochemically detectable surface coat change. 2. Tamoxifen was found to inhibit this in vitro-induced change. The role of Tamoxifen as an inhibitor of implantation is discussed.
摘要
  1. 在17β-雌二醇存在下培养的交配后89小时的小鼠囊胚经历了组织化学可检测的表面被膜变化。2. 发现他莫昔芬可抑制这种体外诱导的变化。讨论了他莫昔芬作为植入抑制剂的作用。

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Tamoxifen inhibition of an in vitro oestradiol-induced surface coat change on mouse blastocysts.他莫昔芬对体外雌二醇诱导的小鼠囊胚表面被膜变化的抑制作用。
Br J Pharmacol. 1977 Aug;60(4):517-9. doi: 10.1111/j.1476-5381.1977.tb07529.x.
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本文引用的文献

1
A new derivative of triphenylethylene: effect on implantation and mode of action in rats.一种三苯乙烯的新衍生物：对大鼠着床的影响及作用方式
J Reprod Fertil. 1967 Feb;13(1):101-19. doi: 10.1530/jrf.0.0130101.
2
Blastocysts in the mouse uterus: the effect of ovariectomy, progesterone and oestrogen.小鼠子宫中的囊胚：卵巢切除术、孕酮和雌激素的影响。
J Endocrinol. 1971 Jul;50(3):515-26. doi: 10.1677/joe.0.0500515.
3
Culture of mouse ova.小鼠卵子培养
J Reprod Fertil Suppl. 1971 Jun;14:7-21.
4
Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary.某些三苯乙烯类化合物对雌二醇体外与子宫和垂体前叶大分子结合的影响。
J Endocrinol. 1972 Feb;52(2):289-98. doi: 10.1677/joe.0.0520289.
5
Blastocyst differentiation in vitro.体外囊胚分化
J Reprod Fertil. 1974 Jul;39(1):243-9. doi: 10.1530/jrf.0.0390243.
6
Change in cell-surface glycoproteins of mouse embryos before implantation.着床前小鼠胚胎细胞表面糖蛋白的变化。
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1645-8. doi: 10.1073/pnas.70.6.1645.
7
Surface coats of the mouse blastocyst and uterus during the preimplantation period.
Anat Rec. 1974 Sep;180(1):31-45. doi: 10.1002/ar.1091800105.
8
Estrogen-induced surface coat and enzyme changes in the implanting mouse blastocyst.雌激素诱导植入期小鼠囊胚的表面被膜及酶变化。
J Embryol Exp Morphol. 1973 Jun;29(3):639-45.
9
Steroidogenesis in rabbit preimplantation embryos.兔着床前胚胎中的类固醇生成。
Proc Natl Acad Sci U S A. 1975 Jan;72(1):298-300. doi: 10.1073/pnas.72.1.298.
10
Estrogen-receptor binding: relationship to estrogen-induced responses.雌激素受体结合：与雌激素诱导反应的关系
J Toxicol Environ Health. 1976 Mar;1(4):561-86. doi: 10.1080/15287397609529359.