他莫昔芬对体外雌二醇诱导的小鼠囊胚表面被膜变化的抑制作用。
Tamoxifen inhibition of an in vitro oestradiol-induced surface coat change on mouse blastocysts.
作者信息
Bloxham P A, Pugh D M
出版信息
Br J Pharmacol. 1977 Aug;60(4):517-9. doi: 10.1111/j.1476-5381.1977.tb07529.x.
Abstract
- Eighty-nine hour post-coitus mouse blastocysts cultured in the presence of oestradiol-17beta underwent a histochemically detectable surface coat change. 2. Tamoxifen was found to inhibit this in vitro-induced change. The role of Tamoxifen as an inhibitor of implantation is discussed.
摘要
- 在17β-雌二醇存在下培养的交配后89小时的小鼠囊胚经历了组织化学可检测的表面被膜变化。2. 发现他莫昔芬可抑制这种体外诱导的变化。讨论了他莫昔芬作为植入抑制剂的作用。
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