Ellis F H, Gibb S P, Balogh K, Schwaber J R
Department of Anatomic Pathology, Deaconess Hospital, Boston, MA 02115, USA.
Dis Esophagus. 1997 Jan;10(1):55-60. doi: 10.1093/dote/10.1.55.
Two cases of a rare combination of conditions, achalasia and adenocarcinoma in Barrett's esophagus are reported. Cancer developed 26 years after the onset of gastroesophageal reflux in one and 30 years after esophagomyotomy in the other. Twenty-one cases of Barrett's esophagus and achalasia have now been reported; adenocarcinoma developed in six patients. Only one has survived more than five years after treatment. Long-term surveillance of patients with achalasia is recommended.
报告了两例贲门失弛缓症与巴雷特食管腺癌这一罕见病症组合的病例。其中一例在胃食管反流发病26年后发生癌变，另一例在食管肌层切开术后30年发生癌变。目前已报告21例巴雷特食管合并贲门失弛缓症的病例；6例患者发生了腺癌。治疗后只有1例存活超过5年。建议对贲门失弛缓症患者进行长期监测。
