拼接未折叠蛋白反应。
Splicing together the unfolded-protein response.
作者信息
Shamu C E
机构信息
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
出版信息
Curr Biol. 1997 Feb 1;7(2):R67-70. doi: 10.1016/s0960-9822(06)00038-8.
PMID:9081665
Abstract
Recent work has identified a transcription factor, Hac1p, in the yeast Saccharomyces cerevisiae, as a component of a pathway that signals to the nucleus the presence of unfolded proteins in the endoplasmic reticulum and has shown that Hac1p expression is regulated by a novel RNA splicing pathway.
摘要
最近的研究工作已在酿酒酵母中鉴定出一种转录因子Hac1p，它是一种向细胞核传递内质网中未折叠蛋白存在信号的通路的组成部分，并且表明Hac1p的表达受一种新型RNA剪接通路调控。
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