类风湿性嗜中性皮病——活动性类风湿性关节炎患者中的一种罕见皮肤病

[Rheumatoid neutrophilic dermatitis--a rare dermatosis in patients with active rheumatoid arthritis].

作者信息

Mrowietz U, Kiene P, Quinkert U

机构信息

Abteilung Dermatologie, Venerologie und Allergologie, Klinikum der Christian-Albrechts-Universität, Kiel.

出版信息

Hautarzt. 1996 Dec;47(12):921-6. doi: 10.1007/s001050050532.

DOI:10.1007/s001050050532

PMID:9081939

Abstract

Rheumatoid neutrophilic dermatitis is a rare dermatologic disorder seen in patients with active rheumatoid arthritis. Clinically firm erythematous 3-5 mm papules are found mainly on the arms, the hips and the proximal thighs. The lesions may be pruritic leading to excoriations and crusts. Histology reveals a dense dermal infiltrate with neutrophilic granulocytes, while leukocytoclasia may be seen, vasculitits is not observed. This overview of rheumatoid neutrophilic dermatitis may help remind the practitioner to include this uncommon disorder in the differential diagnosis of rheumatoid arthritis-related dermatoses.

摘要

类风湿性嗜中性皮病是一种在活动性类风湿性关节炎患者中出现的罕见皮肤病。临床上，主要在手臂、臀部和大腿近端发现质地坚实的3 - 5毫米红斑丘疹。这些皮损可能伴有瘙痒，导致抓痕和结痂。组织学检查显示真皮有密集的嗜中性粒细胞浸润，可见白细胞破碎现象，但未观察到血管炎。对类风湿性嗜中性皮病的概述可能有助于提醒医生在类风湿性关节炎相关皮肤病的鉴别诊断中考虑这种不常见的疾病。