Blauth M, Schmidt U, Dienst M, Knop C, Lobenhoffer P, Tscherne H
Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
Unfallchirurg. 1996 Dec;99(12):925-39. doi: 10.1007/s001130050076.
In this retrospective study we present the long-term results in 89 patients who underwent anterior interbody fusion of acute cervical spine injuries in our institution between 1972 and 1983. There were 23 dislocations, 50 fracture-dislocations and 16 burst fractures without significant posterior lesions. Only 20 patients showed no neurologic symptoms. In all 79 patients who were treated initially in our trauma department, closed reduction was performed as soon as possible. No aggravation of the neurologic conditions by this manoeuvre was observed. The mean time between injury and operation was 7 days (range 0-110 days). In 79 patients an H-plate or one-third-tubular plate was used, and in 10 patients fusion was performed only by bone grafting according to the technique of Robinson [40]. Severe complications, i.e. persistent instability with kyphosis or sagittal dislocation, were found in only 2 of these 10 patients secondary to technical problems. The radiologic results demonstrated a high fusion rate, with fusion in 78 out of the 79 patients. Of the 79 patients treated with plate spondylodeses, 7 devices had to be removed without loss of correction: 6 owing to loosening and 1 to breakage of the plate. Only in one additional case after early hardware removal because of loosening was a loss of correction detected. Of the original 89 patients, 17 had died of causes unrelated to the operation. The mean age of the surviving 72 patients at the time of injury was 36 years (14-83 years). A further 15 patients were lost during follow-up, so that 57 (79%) could be included in the study with a mean follow-up of 11 years, 9 months (10-19 years). The functional results were as follows: Active range of motion was limited between 25 and 50%. 40 patients had no pain at rest, 38 only during motion without need for treatment. A significant correlation between pain and fused segments could not be found. Spontaneous fusion and spondylophytes in adjacent motion segments were seen in 27 patients, again without significant correlation to residual pain. No hypermobility of adjacent motion segments in functional X-rays was seen. 46 patients returned to their former work, 7 were not able to work again secondary to the injury, 4 patients received old-age pension. Improvement of the neurologic deficits in the 37 symptomatic patients was observed in 30 cases (81.1%) according to the "Sunnybrook Cord Injury Scale" [49]; according to the ASIA Neurological Impairment Scale [5] 25 (67.6%) of them improved of at least 1 degree. No correlation could be found between the interval injury to operation and neurologic improvement. With regard to the early stage of the procedure of anterior interbody fusion for traumatic lesions this study shows promising data with high fusion rates and low morbidity, especially for the combination with plate fixation. Further improved within the last 12 years this method offers an excellent alternative for operative treatment of most acute lower cervical spine injuries. Using devices which are not angle stable, special attention should be given to precise bicortical screw fixation.
在这项回顾性研究中,我们呈现了1972年至1983年间在我院接受急性颈椎损伤前路椎间融合术的89例患者的长期结果。其中有23例脱位、50例骨折脱位和16例无明显后方损伤的爆裂骨折。只有20例患者没有神经症状。在最初在我院创伤科接受治疗的所有79例患者中,尽快进行了闭合复位。未观察到该操作使神经状况恶化。受伤至手术的平均时间为7天(范围0 - 110天)。79例患者使用了H形钢板或三分之一管状钢板,10例患者仅根据Robinson [40]的技术进行了植骨融合。这10例患者中仅2例因技术问题出现严重并发症,即伴有后凸或矢状位脱位的持续性不稳定。影像学结果显示融合率很高,79例患者中有78例融合。在接受钢板脊柱融合术治疗的79例患者中,7个器械不得不被取出但未失去矫正:6个因钢板松动,1个因钢板断裂。仅在1例因松动早期取出硬件后的额外病例中检测到矫正丢失。最初的89例患者中,17例死于与手术无关的原因。存活的72例患者受伤时的平均年龄为36岁(14 - 83岁)。随访期间又有15例患者失访,因此57例(79%)可纳入研究,平均随访时间为11年9个月(10 - 19年)。功能结果如下:活动范围受限25%至50%。40例患者静息时无疼痛,38例仅在活动时疼痛但无需治疗。未发现疼痛与融合节段之间存在显著相关性。27例患者在相邻活动节段出现自发融合和骨赘形成,同样与残留疼痛无显著相关性。功能X线检查未发现相邻活动节段有活动度过大的情况。46例患者恢复了原工作,7例因伤无法再工作,4例领取养老金。根据“桑尼布鲁克脊髓损伤量表”[49],37例有症状患者中30例(81.1%)神经功能缺损得到改善;根据美国脊髓损伤协会神经损伤量表[5],其中25例(67.6%)至少改善了1度。受伤至手术的间隔时间与神经功能改善之间未发现相关性。关于创伤性病变前路椎间融合术的早期阶段,本研究显示了有前景的数据,融合率高且发病率低,特别是与钢板固定联合使用时。在过去12年中该方法进一步改进,为大多数急性下颈椎损伤的手术治疗提供了极佳的选择。使用非角度稳定的器械时,应特别注意精确的双皮质螺钉固定。