Blauth M, Schmidt U, Bastian L, Knop C, Tscherne H
Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
Zentralbl Chir. 1998;123(8):919-29.
Lower cervical spine injuries with instability of the anterior and/or posterior column can be treated by anterior interbody fusion and plate fixation. Plates available for anterior instrumentation of the lower cervical spine can be divided into locking or non-locking systems with uni- or bicortical screw purchase. Our biomechanical comparative testing of different screw fixation systems demonstrates improved stability with the use of bicortical purchase. Clinical studies, however, have proven high fusion rates without loss of correction and a low implant related morbidity with the use of unicortical as well of bicortical plate systems. Correct reduction and intraoperative positioning of the unstable cervical spine is crucial to avoid implant related complications. Also, limitations of anterior instrumentation for the treatment of specific lesions of the lower cervical spine have to be considered, e.g. in complex lesions with axial instability or in fracture dislocations with ankylosing spondylitis. Changes or alterations of adjacent segments can be reduced by the use of plates with correct lengths, contact of uninjured adjacent discs with implants should be avoided. A comparative analysis of two patient collectives--89 patients (1972-1983) and 102 patients (1987-1994), all of them treated with bicortical plate fixation--revealed different results in terms of implant failure, operative reduction and loss of correction. All but one surgical fusions had healed radiologically. Implant related complications during the first 3 months after the initial operation were lower in the latter group, only 3 out of 102 patients (3%) with implant loosening versus 7 our of 89 patients (8%) with implant breakage or loosening required surgical revision. In all cases technical errors could be detected. Clinical follow-ups with personal examination was performed in 144 patients: 57 of 72 survivors of series I (79%) after an average time of 11 years 9 months and 87 out of 94 survivors of series II (85%). The radiologic examination revealed 2 patients with screw breakage in series I, one patient with an asymptomatic implant loosening in series II. Only one case was observed with a loss of correction after loosened and early removed hardware. In all other patients there was no difference of radiologic angles between postoperative X-ray and follow-up. 16 patients, 12 of series I, 4 of series II, were fused in a kyphotic position after insufficient preoperative reduction. Radiologic alterations of adjacent segments, i.e. spondylophyts or "spontaneous" fusions, were observed in more than 50% of all patients of both series. However, complaints or persistent pain did not correlate with radiologic findings. Also in both series there was a high percentage of patients with mild, residual neck pain in spite of a very good radiologic result. Only in a very few cases the complaints had to be treated by drugs.
伴有前柱和/或后柱不稳定的下颈椎损伤可通过前路椎间融合和钢板固定进行治疗。可用于下颈椎前路内固定的钢板可分为单皮质或双皮质螺钉固定的锁定或非锁定系统。我们对不同螺钉固定系统进行的生物力学对比测试表明,采用双皮质固定可提高稳定性。然而,临床研究证明,使用单皮质和双皮质钢板系统均具有较高的融合率,且无矫正丢失,与植入物相关的发病率较低。不稳定颈椎的正确复位和术中定位对于避免植入物相关并发症至关重要。此外,还必须考虑前路内固定治疗下颈椎特定损伤的局限性,例如在伴有轴向不稳定的复杂损伤或强直性脊柱炎骨折脱位中。使用长度合适的钢板可减少相邻节段的改变或退变,应避免未受伤的相邻椎间盘与植入物接触。对两个患者群体(89例患者(1972 - 1983年)和102例患者(1987 - 1994年),均采用双皮质钢板固定)进行的对比分析显示,在植入物失败、手术复位和矫正丢失方面结果不同。除1例手术融合外,所有手术融合在影像学上均已愈合。初始手术后前3个月内与植入物相关的并发症在后者组中较低,102例患者中仅有3例(3%)出现植入物松动,而89例患者中有7例(8%)出现植入物断裂或松动需要手术翻修。在所有病例中均能检测到技术失误。对144例患者进行了临床随访及个人检查:系列I的72例幸存者中有57例(79%),平均随访时间为11年9个月;系列II的94例幸存者中有87例(85%)。影像学检查显示,系列I中有2例患者螺钉断裂,系列II中有1例患者植入物松动但无症状。仅观察到1例在植入物松动并早期取出后出现矫正丢失。在所有其他患者中,术后X线与随访时的影像学角度无差异。16例患者,系列I中有12例,系列II中有4例,在术前复位不充分后呈后凸位融合。在两个系列的所有患者中,超过50%观察到相邻节段的影像学改变,即骨赘形成或“自发”融合。然而,主诉或持续性疼痛与影像学表现无关。在两个系列中,尽管影像学结果非常好,但仍有很高比例的患者有轻度残留颈部疼痛。只有极少数病例需要药物治疗。