Iskenderov B G, Tatarchenko I P
Ter Arkh. 1996;68(5):60-3.
ECG investigations of cardiodynamics were performed in 47 patients subjected to isolated ventricular electrocardiostimulation on obsidan treatment. The drug was given in a single dose or in a course. Cardiodynamic effects were evaluated in 3 groups of patients: with hyperkinetic, eukinetic and hypokinetic circulation (17, 19 and 11 patients, respectively). Cardiohemodynamic effects of obsidan are shown to depend on type of circulation and features of intracardiac hemodynamics (fixed cardiac rhythm, atrioventricular dissociation, pathological ventricular asynchronism, valvular blood regurgitation). This potentiates cardiodepressive effects of obsidan in patients with hypokinetic circulation who experience deterioration of cardiac insufficiency.
对47例接受黑曜石治疗的孤立心室电刺激患者进行了心脏动力学的心电图研究。药物采用单剂量或疗程给药。在3组患者中评估了心脏动力学效应：分别为高动力循环、正常动力循环和低动力循环患者（分别为17例、19例和11例）。结果显示，黑曜石的心脏血流动力学效应取决于循环类型和心内血流动力学特征（固定心律、房室分离、病理性心室不同步、瓣膜血液反流）。这增强了黑曜石对低动力循环患者的心脏抑制作用，这些患者的心功能不全恶化。
