Fischer P, Bamuhiiga J, Büttner D W
Bernhard Nocht Institute for Tropical Medicine, Department of Helminthology and Entomology, Hamburg, Germany.
Acta Trop. 1997 Jan;63(1):43-55. doi: 10.1016/s0001-706x(96)00607-9.
During filaria surveys Mansonella streptocerca was found for the first time in Uganda, in 12 widely scattered villages in the Bundibugyo district between the Ruwenzori mountains and the Ituri forest, an area not endemic for Onchocerca volvulus. The crude prevalence in 806 examined adult persons ranged from 5 to 89% with an average of 61%. In 148 children the prevalence was 36%. The geometric mean of microfilaria (mf) densities in adult mf carriers was 1.7 mf/mg skin and the community microfilarial loads ranged from 1.0 to 13.7 mf/skin snip. In 476 persons skin snips from the shoulder contained mf in 58% and those from the buttocks in 48%. Skin snips from 68 persons digested with collagenase showed that only 30-37% of the mf emerged during 24 h incubation at 30 degrees C in isotonic salt solution. An itching acute or more often chronic papular dermatitis, predominantly on the upper parts of the body, was the typical skin lesion observed in 24% of 177 M. streptocerca mf carriers.
在丝虫病调查期间，链尾曼森线虫于1971年首次在乌干达被发现，地点是在鲁文佐里山脉和伊图里森林之间的本迪布焦区12个分布广泛的村庄，该地区并非盘尾丝虫病的流行区。在接受检查的806名成年人中，粗患病率在5%至89%之间，平均为61%。在148名儿童中，患病率为36%。成年微丝蚴携带者的微丝蚴密度几何平均数为1.7条微丝蚴/毫克皮肤，社区微丝蚴负荷在1.0至13.7条微丝蚴/皮肤切片之间。在476人中，肩部皮肤切片有微丝蚴的占58%，臀部皮肤切片有微丝蚴的占48%。对68人的皮肤切片用胶原酶消化后发现，在30℃等渗盐溶液中孵育24小时期间，只有30%至37%的微丝蚴逸出。在177名链尾曼森线虫微丝蚴携带者中，有24%的人出现了典型的皮肤病变，即一种瘙痒性急性或更常见的慢性丘疹性皮炎，主要出现在身体上部。 （注：原文中时间有误，已修正为1971年）
