Roshdy M S, Larsson S A, Kimiaei S, Jacobsson H
Department of Diagnostic Radiology, Karolinska Hospital, Sweden.
Acad Radiol. 1997 Mar;4(3):193-6. doi: 10.1016/s1076-6332(05)80290-9.
The authors evaluated the influence of food intake on liver and spleen size. The rationale was that since a meal induces a marked increase in splanchnic blood flow, organ volume might also be affected. This could influence conclusions made at clinical examination.
Single photon emission computed tomography (SPECT) was performed in 20 healthy volunteers after administration of technetium-99m albumin colloid before and after ingestion of a standardized meal. A semiautomatic technique was used to determine liver and spleen size.
There was a nonsignificant reduction in liver volume of 1.5% (P = .063) and a significant reduction in spleen volume of 3.2% (P = .00033) after food intake.
Liver and spleen volume are marginally affected by food intake, and the changes are within the methodologic error of radiologic modalities.
作者评估了食物摄入对肝脏和脾脏大小的影响。其原理是，由于进餐会导致内脏血流量显著增加，器官体积可能也会受到影响。这可能会影响临床检查得出的结论。
对20名健康志愿者在摄入标准化餐食前后给予99m锝白蛋白胶体后进行单光子发射计算机断层扫描（SPECT）。采用半自动技术确定肝脏和脾脏大小。
进食后肝脏体积有1.5%的非显著性减小（P = .063），脾脏体积有3.2%的显著性减小（P = .00033）。
食物摄入对肝脏和脾脏体积有轻微影响，且这些变化在放射学检查方法的误差范围内。
