Kuna S T, Sant'Ambrogio F B, Sant'Ambrogio G
Department of Internal Medicine, University of Texas Medical Branch, Galveston 77555-0561, USA.
Sleep. 1996 Dec;19(10 Suppl):S180-3. doi: 10.1093/sleep/19.suppl_10.180.
The effects of aerosolized distilled water and isosmolal dextrose in the isolated larynx on laryngeal muscle activity were studied in eight anesthetized dogs. Water aerosol was associated with an increase in peak posterior cricoarytenoid activity but no change in thyroarytenoid activity. Saline or isosmolal dextrose aerosols did not have any effect on the activity of either muscle. The reflex increase in posterior cricoarytenoid activity due to laryngeal negative pressure was enhanced when the negative pressure challenge was repeated following distilled water aerosol. The results suggest that alteration in laryngeal surface liquid composition modifies the response of pressure-responsive laryngeal receptors and, thereby, the reflex activation of airway patency maintaining muscles.
在八只麻醉犬身上研究了雾化蒸馏水和等渗葡萄糖对离体喉部肌肉活动的影响。水雾与环杓后肌峰值活动增加相关，但甲杓肌活动无变化。盐水或等渗葡萄糖气雾剂对这两种肌肉的活动均无任何影响。当在蒸馏水雾化后重复负压刺激时，由于喉部负压引起的环杓后肌活动的反射性增加增强。结果表明，喉部表面液体成分的改变会改变压力敏感型喉部感受器的反应，从而改变维持气道通畅肌肉的反射性激活。
