Douglas N J, Martin S E
Department of Medicine, University of Edinburgh, Royal Infirmary, Scotland, U.K.
Sleep. 1996 Dec;19(10 Suppl):S196-7.
As daytime deficits in sleep apnea/hypopnea syndrome (SAHS) correlate poorly with earlier definitions of arousals, we investigated the relationship between microarousals and sleepiness in 63 patients with SAHS. There was a poor correlation between mean sleep latency and microarousal frequency. To determine whether arousals not detected by current definitions could account for some of the residual variance in normal subjects we used sound to induce "arousals" that were detected by rises in blood pressure but produced no visible EEG change. Such autonomic arousals produced an increase in sleepiness. We conclude that arousals not scored currently on polysomnography may contribute to the sleepiness of patients with SAHS.
由于睡眠呼吸暂停/低通气综合征（SAHS）患者白天的睡眠不足与早期觉醒定义的相关性较差，我们对63例SAHS患者的微觉醒与嗜睡之间的关系进行了研究。平均睡眠潜伏期与微觉醒频率之间的相关性较差。为了确定当前定义未检测到的觉醒是否可以解释正常受试者中的一些残留差异，我们使用声音诱导“觉醒”，这些“觉醒”通过血压升高检测到，但脑电图没有明显变化。这种自主神经觉醒导致嗜睡增加。我们得出结论，目前多导睡眠图未记录的觉醒可能导致SAHS患者的嗜睡。
