Zlotnick C, Warshaw M, Shea M T, Keller M B
Butler Hospital, Brown University, Providence, Rhode Island 02906, USA.
J Consult Clin Psychol. 1997 Apr;65(2):333-6. doi: 10.1037//0022-006x.65.2.333.
This study examined the relationship between a history of trauma and the features and persistence of major depression (MDD) in patients with anxiety disorders. The study found that, among 408 patients with an anxiety disorder and past or current MDD, those patients who reported a history of trauma had a greater number of previous episodes of major depression than those patients without trauma histories. Also, of 174 patients with an anxiety disorder and current major depression, patients who reported histories of trauma, compared with patients who did not report such experiences, were less likely to remit from MDD over a 5-year period. Results suggest that a history of trauma is a risk factor for chronic depression.
本研究调查了创伤史与焦虑症患者中重度抑郁症（MDD）的特征及持续性之间的关系。研究发现，在408例患有焦虑症且有过或目前患有MDD的患者中，报告有创伤史的患者既往重度抑郁发作次数多于无创伤史的患者。此外，在174例患有焦虑症且目前患有重度抑郁症的患者中，报告有创伤史的患者与未报告有此类经历的患者相比，在5年期间从MDD中缓解的可能性较小。结果表明，创伤史是慢性抑郁症的一个危险因素。
