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A one-year study of the evolution of elastase-induced emphysema in hamsters.

作者信息

Snider G L, Sherter C B

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1977 Oct;43(4):721-9. doi: 10.1152/jappl.1977.43.4.721.

DOI:10.1152/jappl.1977.43.4.721
PMID:908690
Abstract
摘要

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Rat and hamster species differences in susceptibility to elastase-induced pulmonary emphysema relate to differences in elastase inhibitory capacity.大鼠和仓鼠对弹性蛋白酶诱导的肺气肿易感性的种属差异与弹性蛋白酶抑制能力的差异有关。
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Elastase-coupled beads as a tool for characterizing localized alveolar tissue destruction associated with the onset of emphysema.弹性蛋白酶偶联珠作为一种工具,用于描述与肺气肿发病相关的局部肺泡组织破坏。
J Appl Physiol (1985). 2013 Jun;114(11):1637-44. doi: 10.1152/japplphysiol.00026.2013. Epub 2013 Apr 4.
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Dysfunctional lung anatomy and small airways degeneration in COPD.
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Int J Chron Obstruct Pulmon Dis. 2006;1(1):3-14. doi: 10.2147/copd.2006.1.1.3.
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Effect of elastase-induced emphysema on the force-generating ability of the diaphragm.弹性蛋白酶诱导的肺气肿对膈肌产生力量能力的影响。
J Clin Invest. 1982 Nov;70(5):978-88. doi: 10.1172/jci110709.
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Histochemical and biochemical correlates of ventilatory muscle fatigue in emphysematous hamsters.肺气肿仓鼠通气肌疲劳的组织化学和生物化学关联
J Clin Invest. 1984 Oct;74(4):1214-20. doi: 10.1172/JCI111530.
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Emphysema alters the deposition pattern of inhaled particles in hamsters.肺气肿会改变仓鼠体内吸入颗粒的沉积模式。
Am J Pathol. 1987 Jul;128(1):19-28.
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Observations on the pathogenesis of chronic airflow obstruction in smokers: implications for the detection of "early" lung disease.吸烟者慢性气流阻塞发病机制的观察:对“早期”肺部疾病检测的启示
Thorax. 1986 Feb;41(2):81-7. doi: 10.1136/thx.41.2.81.
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Contractile and histochemical characteristics of the rabbit diaphragm in elastase-induced emphysema.弹性蛋白酶诱导的兔肺气肿模型中膈肌的收缩和组织化学特征
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High cathepsin B activity in alveolar macrophages occurs with elastase-induced emphysema but not with bleomycin-induced pulmonary fibrosis in hamsters.在仓鼠中,肺泡巨噬细胞中组织蛋白酶B活性升高与弹性蛋白酶诱导的肺气肿有关,但与博来霉素诱导的肺纤维化无关。
Am J Pathol. 1988 Apr;131(1):92-101.