Oöpik V, Timpmann S, Medijainen L, Aleksejeva T
Institute of Exercise Biology, University of Tartu, Estonia.
Ann Nutr Metab. 1996;40(6):359-63. doi: 10.1159/000177945.
The aim of the present study was to assess the effect of creatinine administration on urea metabolism in sedentary and exercised Wistar rats and also on the rate of glycogen resynthesis in the liver and skeletal muscle of endurance-trained animals after exhausting exercise. Creatine treatment for 7 days significantly increased the concentration of urea in blood plasma of sedentary as well as exercised rats and this effect was also maintained in trained animals 24 h after exhausting swimming. The rate of glycogen resynthesis in the liver and skeletal muscle after glycogen-depleting exercise was not modified by creatine administration.
本研究的目的是评估给予肌酐对久坐不动和运动的Wistar大鼠尿素代谢的影响，以及对耐力训练动物在力竭运动后肝脏和骨骼肌中糖原再合成速率的影响。连续7天给予肌酸显著提高了久坐不动和运动大鼠血浆中尿素的浓度，并且在力竭游泳24小时后的训练动物中这种作用仍然存在。给予肌酸并未改变糖原耗竭运动后肝脏和骨骼肌中糖原的再合成速率。
