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台湾地区红霉素耐药性链球菌的高发病率。

High incidence of erythromycin-resistant streptococci in Taiwan.

作者信息

Wu J J, Lin K Y, Hsueh P R, Liu J W, Pan H I, Sheu S M

机构信息

Department of Medical Technology, National Cheng Kung University Medical College, Tainan, Taiwan, Republic of China.

出版信息

Antimicrob Agents Chemother. 1997 Apr;41(4):844-6. doi: 10.1128/AAC.41.4.844.

Abstract

The activities of nine antimicrobial agents against 247 isolates of group B, C, F, and G streptococci and viridans group streptococci were studied by the broth microdilution method. Erythromycin resistance was found in 29.7, 41.7, 81.8, 23.5, and 53.3% of the strains of group B, C, F, and G streptococci and viridans group streptococci tested, respectively. Macrolides are not considered an optimal alternative to penicillin in the treatment of streptococcal infections, at least empirically, in Taiwan.

摘要

采用肉汤微量稀释法研究了9种抗菌药物对247株B、C、F和G组链球菌及草绿色链球菌的抗菌活性。在所检测的B、C、F和G组链球菌及草绿色链球菌菌株中,分别有29.7%、41.7%、81.8%、23.5%和53.3%的菌株对红霉素耐药。在台湾,至少根据经验,大环内酯类药物在治疗链球菌感染方面不被认为是青霉素的最佳替代药物。

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