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北卡罗来纳州可筛查口腔癌诊断阶段的种族差异。

Racial differences in stage at diagnosis of screenable oral cancers in North Carolina.

作者信息

Arbes S J, Slade G D

机构信息

Department of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA.

出版信息

J Public Health Dent. 1996 Fall;56(6):352-4. doi: 10.1111/j.1752-7325.1996.tb02464.x.

DOI:10.1111/j.1752-7325.1996.tb02464.x
PMID:9089532
Abstract

OBJECTIVE

This study examined differences between blacks and whites in stage at diagnosis of screenable oral cancers.

METHODS

Data for 1,137 North Carolina residents with first primary tumors of the oral cavity (excluding the lip and salivary glands) or oropharynx diagnosed from 1990-92 were obtained from the North Carolina Central Cancer Registry. The outcome variable was stage at diagnosis dichotomized as localized and advanced. The explanatory variables were race, sex, age, year diagnosed, tumor site, and county-level socioeconomic and health care resource factors. Bivariate, stratified, and multiple regression analyses were conducted.

RESULTS

In the regression analysis, the odds of advanced stage was 2.1 (95% CI = 1.5, 2.9) times greater for blacks than whites. Other multivariable effects were sex [males compared to females: OR = 1.5 (95% CI = 1.2, 2.0)] and tumor site (oropharynx compared to palate: OR = 4.2 (95% CI = 2.5, 7.0)].

CONCLUSION

Among black and white residents of North Carolina diagnosed with cancer of the oral cavity or oropharynx, blacks had a greater odds of diagnosis at advanced stage.

摘要

目的

本研究调查了可筛查口腔癌确诊阶段黑人和白人之间的差异。

方法

从北卡罗来纳州中央癌症登记处获取了1990 - 1992年诊断为口腔(不包括唇和唾液腺)或口咽原发性肿瘤的1137名北卡罗来纳州居民的数据。结果变量是确诊阶段,分为局限性和晚期。解释变量包括种族、性别、年龄、确诊年份、肿瘤部位以及县级社会经济和医疗资源因素。进行了双变量、分层和多元回归分析。

结果

在回归分析中,黑人处于晚期阶段的几率是白人的2.1倍(95%置信区间 = 1.5, 2.9)。其他多变量效应包括性别[男性与女性相比:比值比 = 1.5(95%置信区间 = 1.2, 2.0)]和肿瘤部位(口咽与腭部相比:比值比 = 4.2(95%置信区间 = 2.5, 7.0)]。

结论

在北卡罗来纳州被诊断患有口腔或口咽癌的黑人和白人居民中,黑人在晚期确诊的几率更高。

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