多聚胞嘧啶区域影响脑心肌炎病毒在朗格汉斯胰岛中的感染进程，但不影响其在心肌中的感染进程。
The poly(C) region affects progression of encephalomyocarditis virus infection in Langerhans' islets but not in the myocardium.
作者信息
Zimmermann A, Botta A, Arnold G, Eggers H J, Nelsen-Salz B
机构信息
Institut für Virologie der Universität zu Köln, Cologne, Germany.
出版信息
J Virol. 1997 May;71(5):4145-9. doi: 10.1128/JVI.71.5.4145-4149.1997.
Abstract
The diabetogenic variant PV2 of encephalomyocarditis virus was cloned, and three recombinants differing in their 5' poly(C) tracts were analyzed. It is shown that the poly(C) region is not essential for infectivity in mice but does influence the virus load and degree of pathological lesions within the Langerhans' islets but not in the myocardium.
摘要
克隆了脑心肌炎病毒的致糖尿病变异体PV2，并分析了三种在其5'聚（C）序列上不同的重组体。结果表明，聚（C）区域对小鼠的感染性不是必需的，但确实会影响朗格汉斯胰岛内的病毒载量和病理损伤程度，而对心肌则无影响。
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本文引用的文献
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