Tidholm A
Albano Animal Hospital of Stockholm, Danderyd, Sweden.
J Small Anim Pract. 1997 Mar;38(3):94-8. doi: 10.1111/j.1748-5827.1997.tb03326.x.
The case records of 151 dogs diagnosed with congenital heart disease were reviewed retrospectively. The most common defect was aortic stenosis, accounting for 35 per cent of all cases, followed by pulmonic stenosis (20 per cent), ventricular septal defect (12 per cent), patent ductus arteriosus (11 per cent), mitral valve dysplasia (8 per cent), tricuspid valve dysplasia (7 per cent), endocardial fibroelastosis (1.9 per cent) and tetralogy of Fallot (0.6 per cent). Fifty-one breeds were represented, with golden retrievers, German shepherd dogs and boxers predominating. No overall sex predilection was obvious. Seventy-five per cent of the dogs were asymptomatic at presentation. The defects most often associated with presenting symptoms, such as dyspnoea, syncope, ascites, failure to grow and depression, were mitral valve dysplasia, atrial septal defect, tricuspid valve dysplasia and endocardial fibroelastosis. The latter presented with the most severe signs of heart failure. In some cases of aortic stenosis and pulmonic stenosis, where the defect could not be accurately visualised with two-dimensional echocardiography, Doppler echocardiographic examination was needed for definitive diagnosis.
对151只被诊断患有先天性心脏病的犬只的病历进行了回顾性研究。最常见的缺陷是主动脉狭窄,占所有病例的35%,其次是肺动脉狭窄(20%)、室间隔缺损(12%)、动脉导管未闭(11%)、二尖瓣发育异常(8%)、三尖瓣发育异常(7%)、心内膜弹力纤维增生症(1.9%)和法洛四联症(0.6%)。涉及51个品种,其中金毛寻回犬、德国牧羊犬和拳师犬占主导。没有明显的总体性别倾向。75%的犬只在就诊时无症状。与出现症状(如呼吸困难、晕厥、腹水、生长发育迟缓及精神沉郁)最常相关的缺陷是二尖瓣发育异常、房间隔缺损、三尖瓣发育异常和心内膜弹力纤维增生症。后者出现最严重的心力衰竭体征。在某些主动脉狭窄和肺动脉狭窄病例中,二维超声心动图无法准确显示缺陷时,需要进行多普勒超声心动图检查以明确诊断。