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印度人群中强迫症患者的脑脊液病毒抗体

Cerebrospinal fluid viral antibodies in obsessive-compulsive disorder in an Indian population.

作者信息

Khanna S, Ravi V, Shenoy P K, Chandramuki A, Channabasavanna S M

机构信息

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

出版信息

Biol Psychiatry. 1997 Apr 15;41(8):883-90. doi: 10.1016/S0006-3223(96)00174-6.

Abstract

Immunoglobulin G viral antibodies for herpes simplex virus type 1, varicella zoster virus, cytomegalovirus, measles, and mumps were studied in 76 subjects with obsessive-compulsive disorder and compared with a control population. There was a significantly higher titer for herpes simplex virus type 1 antibodies. Sera: cerebrospinal fluid ratios were suggestive of intrathecal synthesis.

摘要

对76名强迫症患者的1型单纯疱疹病毒、水痘带状疱疹病毒、巨细胞病毒、麻疹病毒和腮腺炎病毒的免疫球蛋白G病毒抗体进行了研究,并与对照人群进行了比较。1型单纯疱疹病毒抗体的滴度显著更高。血清与脑脊液的比值提示鞘内合成。

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