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人类微生物组在法医学中的影响:一项系统综述。

Impact of the Human Microbiome in Forensic Sciences: a Systematic Review.

作者信息

García Manuel G, Pérez-Cárceles María D, Osuna Eduardo, Legaz Isabel

机构信息

Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence "Campus Mare Nostrum," Faculty of Medicine, University of Murcia, Murcia, Spain.

Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence "Campus Mare Nostrum," Faculty of Medicine, University of Murcia, Murcia, Spain

出版信息

Appl Environ Microbiol. 2020 Oct 28;86(22). doi: 10.1128/AEM.01451-20.

DOI:10.1128/AEM.01451-20
PMID:32887714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7642070/
Abstract

Numerous studies relate differences in microbial communities to human health and disease; however, little is known about microbial changes that occur postmortem or the possible applications of microbiome analysis in the field of forensic science. The aim of this review was to study the microbiome and its applications in forensic sciences and to determine the main lines of investigation that are emerging, as well as its possible contributions to the forensic field. A systematic review of the human microbiome in relation to forensic science was carried out by following PRISMA guidelines. This study sheds light on the role of microbiome research in the postmortem interval during the process of decomposition, identifying death caused by drowning or sudden death, locating the geographical location of death, establishing a connection between the human microbiome and personal items, sexual contact, and the identification of individuals. , , , and play an important role in determining the postmortem interval. can be used to determine the cause of death, and or can be used to ascertain personal identity or geographical location. Several studies point to a promising future for microbiome analysis in the different fields of forensic science, opening up an important new area of research.

摘要

众多研究将微生物群落的差异与人类健康和疾病联系起来;然而,对于死后发生的微生物变化或微生物组分析在法医学领域的可能应用却知之甚少。本综述的目的是研究微生物组及其在法医学中的应用,并确定正在出现的主要研究方向,以及其对法医领域的可能贡献。按照PRISMA指南对与法医学相关的人类微生物组进行了系统综述。这项研究揭示了微生物组研究在分解过程中的死后间隔中的作用,识别溺水或猝死导致的死亡,确定死亡的地理位置,建立人类微生物组与个人物品、性接触以及个体识别之间的联系。 、 、 和 在确定死后间隔方面发挥着重要作用。 可用于确定死因, 或 可用于确定个人身份或地理位置。几项研究指出微生物组分析在法医学不同领域有着光明的未来,开辟了一个重要的新研究领域。

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本文引用的文献

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Alterations in Oral Microbiota in HIV Are Related to Decreased Pulmonary Function.HIV 患者口腔微生物组的改变与肺功能下降有关。
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