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孕妇、胎儿及新生儿的巨细胞病毒感染

Cytomegalovirus infection in the pregnant mother, fetus, and newborn infant.

作者信息

Nelson C T, Demmler G J

机构信息

Department of Pediatrics, University of Kentucky, Lexington, USA.

出版信息

Clin Perinatol. 1997 Mar;24(1):151-60.

PMID:9099507
Abstract

Cytomegalovirus (CMV) is a common virus that infects persons of all ages, races, and backgrounds. Originally described as a rare cause of "cytomegalic inclusion disease," CMV is now known to cause a broad spectrum of illness in the fetus and newborn, with most infections being asymptomatic at birth. This article discusses the epidemiology and diagnosis of CMV infection in pregnant women, the fetus, and the newborn, including recent advances in antenatal diagnosis. In addition, the challenges of treatment and prevention of congenital CMV are explored.

摘要

巨细胞病毒(CMV)是一种常见病毒,可感染所有年龄、种族和背景的人群。CMV最初被描述为“巨细胞包涵体病”的罕见病因,现在已知它会在胎儿和新生儿中引发广泛的疾病,大多数感染在出生时并无症状。本文讨论了孕妇、胎儿和新生儿CMV感染的流行病学和诊断,包括产前诊断的最新进展。此外,还探讨了先天性CMV治疗和预防方面的挑战。

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