Kawahara E, Kimura A, Akasofu M, Kawakami Y, Kobayashi A, Nakanishi I
Department of Medical Technology, School of Allied Medical Professions, Fukui, Japan.
Acta Cytol. 1997 Mar-Apr;41(2):513-8. doi: 10.1159/000332548.
Chordoma that arises along the spinal axis metastasizes to the lung on occasion. Chordoma has been reported to have characteristic cytologic features in fine needle aspiration cytology in primary and metastatic foci.
A 76-year-old female had a tumor on the buttock and tumors in the lung. Exfoliative cytology of the sputum showed cohesive, epithelioid clusters composed of pale-stained, broad cytoplasm with a lacelike pattern, minimal nuclear atypism with anisonucleosis and characteristic mucoid substances.
Cytopathologists should be aware of the possibility of metastatic chordoma when epithelioid tumor cell clusters with benign-looking features embedded in a mucoid substance are detected in aspiration cytology or sputum.
沿脊柱轴发生的脊索瘤偶尔会转移至肺部。据报道，在原发性和转移灶的细针穿刺细胞学检查中，脊索瘤具有特征性的细胞学特征。
一名76岁女性臀部有一肿瘤，肺部也有肿瘤。痰液脱落细胞学检查显示，细胞呈黏附性，为上皮样细胞团，由淡染、宽大的细胞质组成，呈花边状，核异型性极小，有核大小不均，且有特征性的黏液样物质。
当在穿刺细胞学检查或痰液中检测到嵌入黏液样物质中的具有良性外观特征的上皮样肿瘤细胞团时，细胞病理学家应意识到转移性脊索瘤的可能性。
