Drzewiecki K T
Scand J Plast Reconstr Surg. 1977;11(1):9-16. doi: 10.3109/02844317709025490.
The surface morphology of the melanoma cell in situ is summarized with regard to a study undertaken to elucidate the appearance of melanocytes and their differentiation in the surroundings of the malignant melanoma. Despite a non uniform cell pattern, several characteristic changes were found. The cells were 2-3 times the size of normal melanocytes, a number being differentiated by dendrites. The surface of the cell was marked by a numerous extensions, a number of which had differentiations that indicate a special function, though some smooth-surfaced cells were also found. It is possible that cell surfaces with many bulges and extensions are an expression of an unstable, undulating surface which could be of significance for the uncontrolled growth and metastasis of tumours.
关于一项旨在阐明恶性黑色素瘤周围黑素细胞的外观及其分化情况的研究，总结了原位黑色素瘤细胞的表面形态。尽管细胞模式并不均匀，但仍发现了一些特征性变化。这些细胞的大小是正常黑素细胞的2至3倍，许多细胞通过树突进行分化。细胞表面有许多延伸部分，其中一些具有表明特殊功能的分化，不过也发现了一些表面光滑的细胞。具有许多凸起和延伸部分的细胞表面可能是不稳定、起伏表面的一种表现，这可能对肿瘤的无控制生长和转移具有重要意义。
