Hoffman D J, Niyogi S K
Science. 1977 Nov 4;198(4316):513-4. doi: 10.1126/science.910143.
Five metal salts (lead, cadmium, cobalt, copper, and manganese),which are mutagenic or carcinogenic, decreasing the fidelity of DNA synthesis in vitro, stimulated chain initiation of RNA synthesis at concentrations that inhibited overall RNA synthesis. In contrast, other metal salts (zinc, magnesium, lithium, sodium,and potassium) not in this category inhibited chain initiation of RNA synthesis at concentrations that inhibited overall RNA synthesis.
五种具有致突变性或致癌性、在体外会降低DNA合成保真度的金属盐（铅、镉、钴、铜和锰），在抑制总体RNA合成的浓度下刺激了RNA合成的链起始。相比之下，不在此列的其他金属盐（锌、镁、锂、钠和钾）在抑制总体RNA合成的浓度下抑制了RNA合成的链起始。
