三名HLA B27抗原阴性的祖鲁族男性的强直性脊柱炎
Ankylosing spondylitis in three Zulu men negative for the HLA B27 antigen.
作者信息
Chalmers I M, Seedat Y K, Mudaliar M Y
出版信息
S Afr Med J. 1977 Sep 24;52(14):567-9.
PMID:910198
Abstract
Three cases of ankylosing spondylitis in Zulu men are presented. They are of interest in that all 3 patients were negative for HLA B27, a tissue-typing antigen that is present in the vast majority of Caucasians with the disease. We draw attention to the rarity of ankylosing spondylitis and also of the B27 antigen in Blacks and offer some postulates on the relationship between these two phenomena.
摘要
本文报告了3例祖鲁族男性强直性脊柱炎病例。这3例病例值得关注，因为所有3例患者的HLA B27均为阴性，而在绝大多数患有该疾病的白种人中都存在这种组织分型抗原。我们提请注意强直性脊柱炎在黑人中的罕见性以及B27抗原在黑人中的罕见性，并对这两种现象之间的关系提出一些假设。
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