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[大鼠慢性γ射线照射下下丘脑的儿茶酚胺能系统]

[The catecholaminergic system in the hypothalamus in the chronic gamma irradiation of rats].

作者信息

Slozhenikina L V, Makar V R, Kolomiĭtseva I K

出版信息

Radiats Biol Radioecol. 1997 Jan-Feb;37(1):25-9.

PMID:9102124
Abstract

Drastic changes in the level of catecholamines (dophamine and noradrenaline) in the central regulatory area of the sympathetic-adrenal system-hypothalamus--caused by continuous gamma irradiation of rats were observed. The irradiation was performed with the doses of 9 to 165 cGy at a rate of 1.1 cGy/day and with the doses of 17 to 315 cGy at a rate of 2.1 cGy/day. Dose dependences of the effect were of a non-monotonic nature. Conclusion was made of a high sensitivity of the sympathetic-adrenal system to the action of chronic low-dose gamma irradiation.

摘要

观察到,由于对大鼠进行持续的γ射线照射,导致交感-肾上腺系统的中枢调节区域——下丘脑内的儿茶酚胺(多巴胺和去甲肾上腺素)水平发生了剧烈变化。照射剂量为9至165厘戈瑞,照射速率为每天1.1厘戈瑞;以及剂量为17至315厘戈瑞,照射速率为每天2.1厘戈瑞。该效应的剂量依赖性呈非单调性质。得出的结论是,交感-肾上腺系统对慢性低剂量γ射线照射的作用具有高度敏感性。

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1
[The catecholaminergic system in the hypothalamus in the chronic gamma irradiation of rats].[大鼠慢性γ射线照射下下丘脑的儿茶酚胺能系统]
Radiats Biol Radioecol. 1997 Jan-Feb;37(1):25-9.
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