Ronchetto F, Vineis C, Musso V
Divisione di Medicina III, Ospedale di Castellamonte, USL 9 Ivrea, Torino.
Recenti Prog Med. 1996 Dec;87(12):592-3.
The authors--which publish an overview about Whipple's disease in this issue, pages 609-611--report the case of a 67-year-old man admitted to the hospital because of migratory arthralgia, low-grade fever, lymphadenopathy, diarrhea, and impaired intestinal absorption. The microscopical examination of the intestinal mucosa showed an infiltration of the lamina propria by foamy PAS-positive macrophages. The patient was treated with antibiotics for 1 year and obtained clinical remission. The authors discuss if it is opportune, in subjects with this disease, to repeat the small-bowel biopsies at the end of the antibiotic treatment in absence of clinical manifestations of relapse or not.
在本期杂志第609 - 611页发表了一篇关于惠普尔病概述的作者们,报告了一例67岁男性因游走性关节痛、低热、淋巴结病、腹泻及肠道吸收功能受损而入院的病例。肠道黏膜的显微镜检查显示固有层有泡沫状PAS阳性巨噬细胞浸润。该患者接受了1年的抗生素治疗并获得临床缓解。作者们讨论了对于患有这种疾病的患者,在抗生素治疗结束且无复发临床表现的情况下,重复进行小肠活检是否合适。