Patten E, Beck C E, Scholl C, Stroope R A, Wukasch C
Transfusion. 1977 Sep-Oct;17(5):517-20. doi: 10.1046/j.1537-2995.1977.17578014595.x.
Autoimmune hemolytic anemia (hemoglobin 5.2 g, reticulocyte count 31.0 per cent) developed in a 53-year-old hypertensive woman who was taking Aldomet. Both the patient's serum and the eluate prepared from her red blood cells contained an antibody with anti-Jka specificity. Rapid sustained improvement in the anemia occurred after cessation of Aldomet and a two week course of prednisone therapy. Eight months later, anti-Jka was no longer detectable in the patient's serum and the direct antiglobulin test was nonreactive.
一名53岁正在服用甲基多巴的高血压女性患者发生了自身免疫性溶血性贫血（血红蛋白5.2 g，网织红细胞计数31.0%）。患者血清及从其红细胞制备的洗脱液中均含有抗Jka特异性抗体。停用甲基多巴并进行为期两周的泼尼松治疗后，贫血迅速持续改善。8个月后，患者血清中不再能检测到抗Jka，直接抗人球蛋白试验无反应。
