Mitić-Milinkić M, Milutinović R, Vukcević M, Miladinović D
Institute of Pulmonary Diseases and Tuberculosis, University Clinical Center, Belgrade.
Srp Arh Celok Lek. 1996 Mar-Apr;124(3-4):62-4.
Pulmonary function in 25 patients with a severe degree of kyphoscoliosis was studied. Severe restrictive ventilatory insufficiency and hypoxaemic-hypercapnic respiratory failure were discovered. Isolated deformities of the vertebral column were diagnosed in 15 patients while ten patients, apart from diagnosed kyphoscoliosis, had associated chronic obstructive pulmonary diseases. Significant differences in pulmonary function impairment between these two groups, i.e. patients with associated chronic obstructive pulmonary disease, were observed. This indicates that associated pulmonary disease accelerates the development and course of respiratory failure. Respiratory blood gas analysis in 11 patients over the course of two years showed significant worsening of hypoxaemia and hypercapnia, which implies that in patients with kyphoscoliosis the disease has a rapid progression once the respiratory failure develops.
对25例重度脊柱后凸侧弯患者的肺功能进行了研究。发现存在严重的限制性通气功能不全和低氧血症-高碳酸血症性呼吸衰竭。15例患者被诊断为单纯脊柱畸形，而另外10例患者除了被诊断为脊柱后凸侧弯外，还伴有慢性阻塞性肺疾病。观察到这两组患者（即伴有慢性阻塞性肺疾病的患者）在肺功能损害方面存在显著差异。这表明相关的肺部疾病会加速呼吸衰竭的发展和进程。对11例患者进行了为期两年的呼吸血气分析，结果显示低氧血症和高碳酸血症显著恶化，这意味着脊柱后凸侧弯患者一旦发生呼吸衰竭，病情进展迅速。
