Djordjević V, Velicković R, Avramović M, Savić V
Institute of Nephrology and Hemodialysis, Faculty of Medicine, Nish.
Srp Arh Celok Lek. 1996;124 Suppl 1:62-4.
In a period of 10 years we performed renal biopsies in 13 patients with systemic lupus erythematosis, the results showed mild changes and focal glomerulonephritis in 30%, diffuse glomerulonephritis in 23% and membranous nephropathy and sclerotic glomerulonephritis in 15% of patients. In the follow-up period three patients died. Prognosis of severe lupus nephritis is better nowadays because of improved therapy. Adverse effects of the applied therapy should not be overlooked while arterial hypertension should be suppressed.
在10年的时间里,我们对13例系统性红斑狼疮患者进行了肾活检,结果显示30%的患者有轻度改变和局灶性肾小球肾炎,23%的患者有弥漫性肾小球肾炎,15%的患者有膜性肾病和硬化性肾小球肾炎。在随访期间,有3例患者死亡。由于治疗方法的改进,重症狼疮性肾炎的预后如今有所改善。在抑制动脉高血压的同时,不应忽视所用治疗方法的不良反应。