Ulisko I N, Baturo A P, Romanenko E E, Stepanova M V, Ratiner Iu A
Zh Mikrobiol Epidemiol Immunobiol. 1996 Nov-Dec(6):7-10.
Different E. coli of 0-groups, enteropathogenic (EPEC), enteroinvasive, enterotoxigenic (ETEC) and diarrheogenic in sporadic child diarrhea (DESCD), regarded as the causative agents of enteric infections, were detected in 70-80% of cases (1,146 E.coli carriers) in the feces of child and adult patients with acute enteric infections (AEI) irrespective of their age; in 35% of cases the same patient had a combination of two or more varieties of EPEC, ETEC or DESCD. Only EPE were excreted by 3.5-11.3% of patients, depending on their age; only ETEC were excreted by 1.7-3.4% of patients and only DESCD, by 23.1-32.8%. In 30-40% of cases diarrheogenic E.coli of the corresponding 0-groups were isolated as monocultures. The complex of bacteriological criteria, serving as the basis for the diagnostics of AEI (the necessity of the quantitative and qualitative characterization of the contamination of the seed material, E.coli serological labeling, the determination of E.coli pathogenicity factors) is discussed.
在患有急性肠道感染（AEI）的儿童和成人患者粪便中，70%-80%的病例（1146例大肠杆菌携带者）检测到不同0群的大肠杆菌，包括肠道致病性大肠杆菌（EPEC）、肠侵袭性大肠杆菌、产肠毒素大肠杆菌（ETEC）以及散发性儿童腹泻（DESCD）中的致泻性大肠杆菌，这些被视为肠道感染的病原体，且与患者年龄无关；35%的病例中，同一患者存在两种或更多种EPEC、ETEC或DESCD的组合。仅EPE由3.5%-11.3%的患者排出，具体取决于其年龄；仅ETEC由1.7%-3.4%的患者排出，仅DESCD由23.1%-32.8%的患者排出。在30%-40%的病例中，相应0群的致泻性大肠杆菌以纯培养物形式分离出来。本文讨论了作为AEI诊断基础的细菌学标准组合（种子材料污染的定量和定性表征的必要性、大肠杆菌血清学标记、大肠杆菌致病因子的测定）。
