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产后甲状腺功能障碍

Postpartum thyroid dysfunction.

作者信息

Browne-Martin K, Emerson C H

机构信息

Division of Endocrinology and Metabolism, University of Massachusetts Medical Center, Worcester 01655, USA.

出版信息

Clin Obstet Gynecol. 1997 Mar;40(1):90-101. doi: 10.1097/00003081-199703000-00010.

DOI:10.1097/00003081-199703000-00010
PMID:9103952
Abstract

Four disorders of the postpartum period are associated with thyroid dysfunction. The most common is PPT. Although recovery from thyroid dysfunction often occurs in PPT, many patients eventually develop permanent hypothyroidism. Postpartum Graves' Disease is less common than PPT, but it is not unusual. Whereas antithyroid drugs are indicated for postpartum Graves' Disease, they are not useful in PPT. Although they are rare, lymphocytic hypophysitis and postpartum pituitary infarction are important entities because they cause deficiencies of many critical hormones. The autoimmune nature of PPT, postpartum Graves' disease, and lymphocytic hypophysitis highlights the unique effects of pregnancy on the immune system.

摘要

产后甲状腺功能障碍相关的产后疾病有四种。最常见的是产后甲状腺炎(PPT)。虽然甲状腺功能障碍通常会在产后甲状腺炎中恢复,但许多患者最终会发展为永久性甲状腺功能减退。产后格雷夫斯病比产后甲状腺炎少见,但并不罕见。抗甲状腺药物适用于产后格雷夫斯病,但对产后甲状腺炎无效。淋巴细胞性垂体炎和产后垂体梗死虽然罕见,但却是重要的病症,因为它们会导致多种关键激素缺乏。产后甲状腺炎、产后格雷夫斯病和淋巴细胞性垂体炎的自身免疫性质凸显了妊娠对免疫系统的独特影响。

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