Chand S P, Chand P
Department of Behavioural Sciences, College of Medicine, Sultan Qaboos University, Al-Khod, Muscat, Sultanate of Oman.
Singapore Med J. 1996 Dec;37(6):663-4.
Brain damage has been reported to be associated with the onset of panic disorder. We report a case of panic disorder with agoraphobia (PDA) after recovery from tuberculous meningitis (TBM). The CT brain showed cerebral oedema and basal meningeal enhancement. On recovery from the TBM, the patient developed PDA as well as features of depression. She was treated with alprazolam, amitryptline and underwent behaviour therapy over a period of 18 months. At the end of this period, the patient showed improvement but had not reached her pre-morbid level of functioning. The possibilities of brain damage as aetiological factors for PDA are discussed.
据报道，脑损伤与惊恐障碍的发病有关。我们报告一例结核性脑膜炎（TBM）康复后出现伴有广场恐惧症的惊恐障碍（PDA）的病例。脑部CT显示脑水肿和基底脑膜强化。TBM康复后，该患者出现了PDA以及抑郁症状。她接受了阿普唑仑、阿米替林治疗，并在18个月的时间里接受了行为疗法。在此阶段结束时，患者有所改善，但尚未恢复到病前的功能水平。本文讨论了脑损伤作为PDA病因的可能性。
