Hepple R T, Mackinnon S L, Goodman J M, Thomas S G, Plyley M J
Department of Physiology, University of Toronto, Ontario, Canada.
J Appl Physiol (1985). 1997 Apr;82(4):1305-10. doi: 10.1152/jappl.1997.82.4.1305.
Both aerobic training (AT) and resistance training (RT) may increase aerobic power (VO2peak) in the older population; however, the role of changes in the capillary supply in this response has not been evaluated. Twenty healthy men (age 65-74 yr) engaged in either 9 wk of lower body RT followed by 9 wk of AT on a cycle ergometer (RT-->AT group) or 18 wk of AT on a cycle ergometer (AT-->AT group). RT was performed three times per week and consisted of three sets of four exercises at 6-12 repetitions maximum. AT was performed three times per week for 30 min at 60-70% heart rate reserve. VO2peak was increased after both RT and AT (P < 0.05). Biopsies (vastus lateralis) revealed that the number of capillaries per fiber perimeter length was increased after both AT and RT (P < 0.05), paralleling the changes in VO2peak, whereas capillary density was increased only after AT (P < 0.01). These results, and the finding of a significant correlation between the change in capillary supply and VO2peak (r = 0.52), suggest the possibility that similar mechanisms may be involved in the increase of VO2peak after high-intensity RT and AT in the older population.
有氧训练（AT）和抗阻训练（RT）都可能提高老年人群的有氧能力（最大摄氧量，VO2peak）；然而，毛细血管供应变化在这一反应中的作用尚未得到评估。20名健康男性（年龄65 - 74岁），一组进行9周的下肢抗阻训练，随后在功率自行车上进行9周的有氧训练（RT→AT组），另一组在功率自行车上进行18周的有氧训练（AT→AT组）。抗阻训练每周进行3次，包括四组练习，每组进行6 - 12次最大重复次数。有氧训练每周进行3次，每次30分钟，心率储备为60 - 70%。抗阻训练和有氧训练后最大摄氧量均增加（P < 0.05）。活检（股外侧肌）显示，抗阻训练和有氧训练后每纤维周长的毛细血管数量均增加（P < 0.05），与最大摄氧量的变化平行，而毛细血管密度仅在有氧训练后增加（P < 0.01）。这些结果，以及毛细血管供应变化与最大摄氧量之间存在显著相关性（r = 0.52）这一发现，表明在老年人群中，高强度抗阻训练和有氧训练后最大摄氧量增加可能涉及相似的机制。
