Burchardt U, Mantel E, Krebbel I
Z Gesamte Inn Med. 1977 Jun 15;32(12):285-8.
In patients with chronic pyelonephritis (n = 17), nephrotic syndrome (n = 7) and hyperthyroidism in comparison to a reference group of healthy persons (n = 17) total activity and isoenzymes of the lactate dehydrogenase in the urine were determined. Only in patients with pyelonephritis is not regularly increased activity of the total lactate dehydrogenase a clear increased excretion of the isoenzymes IV and V is established. The isoenzyme pattern shows a dependence on the content of leucocytes in the urine and normalizes in renal infections only in a therapeutic effect.
对17例慢性肾盂肾炎患者、7例肾病综合征患者和甲状腺功能亢进患者,与17例健康人组成的参照组相比,测定了尿中乳酸脱氢酶的总活性和同工酶。仅在肾盂肾炎患者中,总乳酸脱氢酶活性并非经常升高,但已确定同工酶IV和V的排泄明显增加。同工酶模式显示出对尿中白细胞含量的依赖性,且仅在治疗有效时,肾脏感染时才会恢复正常。