Mahrle C, Bolling R, Gartmann H
Z Hautkr. 1977 Sep 1;52(17):897-905.
A 59 years old woman who was admitted in our hospital had developed two primary melanomas at the lower leg during an interval of 15 years. The histologic diagnosis was a verrucous lentino maligna melanoma for both tumors. The differentiation from superficial spreading melanoma may be difficult. Interestingly enough, in our patient the formation of the new primary melanoma occurred simultaneously with the regression of the older one. In consequence, it seems that regression of a melanoma may not prevent from progression of the disease or from formation of a new primary melanoma.
一名59岁女性因小腿处15年间先后出现两个原发性黑色素瘤而入住我院。两个肿瘤的组织学诊断均为疣状雀斑样恶性黑色素瘤。与浅表扩散性黑色素瘤进行鉴别可能存在困难。有趣的是，在我们的患者中，新的原发性黑色素瘤的形成与较老的黑色素瘤的消退同时发生。因此，似乎黑色素瘤的消退并不能阻止疾病进展或新的原发性黑色素瘤的形成。
