Doull I J, Bright J, Yogeswaran P, Howarth P H
University Medicine, Southampton General Hospital, UK.
Allergy. 1997 Feb;52(2):220-3. doi: 10.1111/j.1398-9995.1997.tb00979.x.
There is a lack of consensus as to the best way to quantify settled house-dust mite Der p 1 allergen from planar and nonplanar surfaces. To investigate the most appropriate measure of settled house-dust mite Der p 1 allergen, we determined the relationship between Der p 1 allergen content and collected dust weight from planar-surface (mattress) and nonplanar-surface (living-room) samples in 58 homes. There was a direct relationship between Der p 1 content and dust weight for both planar-surface (mattress, n = 217) samples (r = 0.50, P < 0.0001) and nonplanar-surface (living-room, n = 48) samples (r = 0.61, P < 0.0001). Correction for the surface area of the planar surface (mattress) vacuum-cleaned resulted in no additional benefit. We conclude that expression of Der p 1 levels per weight of collected dust appears to be the best method for both planar and nonplanar surfaces.
对于如何以最佳方式量化平面和非平面表面上定居的屋尘螨Der p 1变应原，目前尚无共识。为了研究定居的屋尘螨Der p 1变应原的最合适测量方法，我们测定了58户家庭中平面表面（床垫）和非平面表面（客厅）样本的Der p 1变应原含量与收集到的灰尘重量之间的关系。对于平面表面（床垫，n = 217）样本（r = 0.50，P < 0.0001）和非平面表面（客厅，n = 48）样本（r = 0.61，P < 0.0001），Der p 1含量与灰尘重量之间均存在直接关系。对经真空清洁的平面表面（床垫）的表面积进行校正并无额外益处。我们得出结论，每收集到的灰尘重量中Der p 1水平的表达似乎是平面和非平面表面的最佳方法。
