Wiener P, Alexopoulos G S, Kakuma T, Meyers B S, Rosenthal E, Chester J
Cornell University Medical College, White Plains, NY 10605, USA.
Am J Geriatr Psychiatry. 1997 Spring;5(2):116-25.
The authors assessed the limits of reliable history-taking in depressed elderly patients (N = 20) with some cognitive impairment. Each subject and an informant was interviewed with structured instruments by two trained raters. An expert panel formed consensus judgments after reviewing information reported by the patients, the informants, and each of the clinical raters. Intraclass correlation between the two raters was 0.99 for the duration of depressive episodes and 0.88 for age at onset. The raters agreed on the duration of major depressive episodes in 85% of cases and on age at onset in 80% of cases. The duration of previous depressive episodes and age at depression onset cannot always be determined reliably even when informants and structured interviews are used. Greater difficulties may be encountered in patients with minor depression or chronic intermittent depression and early-onset depression. Clinicians should obtain history from as many reliable sources as possible and critically evaluate this information while considering the entire clinical picture. The aggregate kappa statistic can provide a clinically meaningful way of assessing interrater reliability of psychopathological constructs for which several definitions are used.
作者评估了存在一定认知障碍的老年抑郁症患者(N = 20)可靠病史采集的局限性。两名经过培训的评估者使用结构化工具对每位受试者及其知情者进行访谈。一个专家小组在审查患者、知情者以及每位临床评估者报告的信息后形成共识判断。两位评估者之间,抑郁发作持续时间的组内相关系数为0.99,发病年龄的组内相关系数为0.88。评估者在85%的病例中对重度抑郁发作的持续时间达成一致,在80%的病例中对发病年龄达成一致。即使使用知情者和结构化访谈,既往抑郁发作的持续时间和抑郁发病年龄也并非总能可靠确定。对于轻度抑郁、慢性间歇性抑郁和早发性抑郁患者,可能会遇到更大困难。临床医生应从尽可能多的可靠来源获取病史,并在考虑整个临床情况时审慎评估这些信息。总体卡帕统计量可为评估使用多种定义的精神病理学结构的评估者间信度提供一种具有临床意义的方法。