Lenze Eric J, Wetherell Julie Loebach
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
Dialogues Clin Neurosci. 2011;13(4):381-99. doi: 10.31887/DCNS.2011.13.4/elenze.
Neurodevelopmental changes over the lifespan, from childhood through adulthood into old age, have important implications for the onset, presentation, course, and treatment of anxiety disorders. This article presents data on anxiety disorders as they appear in older adults, as compared with earlier in life. In this article, we focus on aging-related changes in the epidemiology, presentation, and treatment of anxiety disorders. Also, this article describes some of the gaps and limitations in our understanding and suggests research directions that may elucidate the mechanisms of anxiety disorder development later in life. Finally we describe optimal management of anxiety disorders across the lifespan, in "eight simple steps" for practitioners.
从童年到成年再到老年,整个生命周期中的神经发育变化对焦虑症的发病、表现、病程及治疗都具有重要意义。本文呈现了与生命早期相比,老年人中出现的焦虑症数据。在本文中,我们聚焦于焦虑症在流行病学、表现及治疗方面与衰老相关的变化。此外,本文描述了我们理解中的一些差距和局限,并提出了一些研究方向,这些方向可能会阐明晚年焦虑症发展的机制。最后,我们为从业者提供了“八个简单步骤”,描述了整个生命周期中焦虑症的最佳管理方法。