小鼠乳腺肿瘤病毒与野生小鼠的乳腺肿瘤发生
Mouse mammary tumor virus and mammary tumorigenesis in wild mice.
作者信息
Imai S
机构信息
Nara Prefectural Institute of Public Health, Japan.
出版信息
Pathol Int. 1996 Dec;46(12):919-32. doi: 10.1111/j.1440-1827.1996.tb03570.x.
Abstract
The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV. Finally, the viral etiology of human breast cancer will be discussed.
摘要
本文综述了目前关于小鼠乳腺肿瘤病毒（MMTV）前病毒基因组分布以及MMTV在小鼠中引发乳腺肿瘤机制的知识，主要聚焦于亚洲野生小鼠。总结了早期关于MMTV传播方式的相关发现，以勾勒出MMTV的生物学概况。最后，将讨论人类乳腺癌的病毒病因。
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